Donahue, S. M., Kleinman, K. P., Gillman, M. W., & Oken, E., "Trends in birth weight and gestational length among singleton term births in the United States: 1990-2005," Obstetrics and Gynecology, 2010, 115(2 Pt 1), 357-364. DOI: 10.1097/AOG.0b013e3181cbd5f5.
ABSTRACT:
OBJECTIVE: To estimate changes over time in birth weight for gestational age and in gestational length among term singleton neonates born from 1990 to 2005.
METHODS: We used data from the U.S. National Center for Health Statistics for 36,827,828 singleton neonates born at 37-41 weeks of gestation, 1990-2005. We examined trends in birth weight, birth weight for gestational age, large and small for gestational age, and gestational length in the overall population and in a low-risk subgroup defined by maternal a... Read more
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Catov, J. M., Lee, M., Roberts, J. M., Xu, J., & Simhan, H. N., "Race Disparities and Decreasing Birth Weight: Are All Babies Getting Smaller?," American Journal of Epidemiology, 2016, 183(1), 15-23. DOI: 10.1093/aje/kwv194.
ABSTRACT:
The mean infant birth weight in the United States increased for decades, but it might now be decreasing. Given race disparities in fetal growth, we explored race-specific trends in birth weight at Magee-Womens Hospital, Pittsburgh, Pennsylvania, from 1997 to 2011. Among singleton births delivered at 37-41 weeks (n = 70,607), we evaluated the proportions who were small for gestational age and large for gestational age and changes in mean birth weights over time. Results were stratified by maternal race/ethnicity. Since 1997, the number of infants ... Read more
Milesi, Maria M, Lorenz, Virginia, Pacini, Guillermina, Repetti, Maria R, Demonte, Luisina D, Varayoud, Jorgelina, & Luque, Enrique H, "Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats," Archives of Toxicology, 2018, 92(8), 2629-2643. DOI: 10.1007/s00204-018-2236-6.
ABSTRACT:
Glyphosate-based herbicides (GBHs) are the most globally used herbicides raising the risk of environmental exposition. Here, we investigated whether perinatal exposure to low doses of a GBH alters the female reproductive performance, and/or induced second-generation effects related to congenital anomalies or growth alterations. Pregnant rats (F0) received a GBH through food, in a dose of 2 mg (GBH-LD: GBH-l... Read more
Sheela Sathyanarayana MD MPH, Olga Basso PhD, Catherine J. Karr MD PhD MS, Paula Lozano MD MPH, Michael Alavanja PhD, Dale P. Sandler PhD & Jane A. Hoppin ScD, "Maternal Pesticide Use and Birth Weight in the Agricultural Health Study," Journal of Agromedicine, 15:2, 2010, DOI: 10.1080/10599241003622699
ABSTRACT:
Studies examining the association between maternal pesticide exposure and low birth weight yield conflicting results. The authors examined the association between maternal pesticide use and birth weight among women in the Agricultural Health Study, a large study of pesticide applicators and their spouses in Iowa and North Carolina. The authors evaluated self-reported pesticide use of 27 individual pesticides in relation to birth weight among 2246 farm women whose most ... Read more
S. Parvez, R. R. Gerona, C. Proctor, M. Friesen, J. L. Ashby, J. L. Reiter, Z. Lui, and P. D. Winchester, "Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study," Environmental Health, 17:23, March 9, 2018, DOI: 10.1186/s12940-018-0367-0.
ABSTRACT:
BACKGROUND: Glyphosate (GLY) is the most heavily used herbicide worldwide but the extent of exposure in human pregnancy remains unknown. Its residues are found in the environment, major crops, and food items that humans, including pregnant women, consume daily. Since GLY exposure in pregnancy may also increase fetal exposure risk, we designed a birth-cohort study to determine exposure frequency, potential exposure pathways, and associations with fetal growth indicators and pregnancy ... Read more
Winchester P, Proctor C, Ying J, "County-level pesticide use and risk of shortened gestation and preterm birth," Acta Paediatrica, 2016, 105:3, DOI: 10.1111/apa.13288.
ABSTRACT:
AIM: This study assesses the association between pesticide exposure in pregnancy, preterm birth (PTB) and shortened gestation.
METHODS: Pregnancy information was abstracted from the Centers for Disease Control (CDC) Non-Public Use Natality Datasets 1990-2005. Pesticide use in maternal county of residence was calculated using California Pesticide Use Reporting (PUR) data 1990-2005. Counties were ranked by pesticide use, and birth months were sorted by peak (May-June) or nonpeak (other months) pesticide use. Multivariate logistical regression models were used.
RESULTS: Counties with higher pesticide us... Read more
Winchester PD, Parvez S, Proctor C, Ying J, Gerona RR, "Fetal Exposure to Glyphosate," Presentation, Pediatric Academic Societies, May 6-7, 2017, San Francisco, California.
SUMMARY:
Measured glyphosate in pregnant women to estimate fetal exposure and monitor potential adverse effects on pregnancy outcomes. Glyphosate was present in 91% of the urine samples and higher glyphosate levels were correlated with shorter pregnancies and lower birth weights. FULL TEXT Read more
Cohn BA, La Merrill M, Krigbaum NY, Yeh G, Park JS, Zimmermann L, Cirillo PM, “DDT Exposure in Utero and Breast Cancer,” Journal of Clinical Endocrinology and Metabolism, 2015, 100:8, doi: 10.1210/jc.2015-1841.
ABSTRACT:
CONTEXT: Currently no direct evidence links in utero dichlorodiphenyltrichloroethane (DDT) exposure to human breast cancer. However, in utero exposure to another xenoestrogen, diethylstilbestrol, predicts an increased breast cancer risk. If this finding extends to DDT, it could have far-reaching consequences. Many women were heavily exposed in utero during widespread DDT use in the 1960s. They are now reaching the age of heightened breast cancer risk. DDT exposure persists and use continues in Africa and Asia without clear knowledge of the consequences for the nex... Read more